proteinmpnn
Inverse-fold backbones into sequences, redesign one chain while fixing interface residues, or sweep temperatures.
What does this skill do?
Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding.
Why is it worth installing?
Unlike single-output tools, it sweeps temperature and locks interface residues, plugging straight into RFdiffusion backbones.
How do you install it?
git clone --depth 1 https://github.com/aipoch/open-science.git Then point your agent at the skill directory.
Where does it come from?
Repository: aipoch/open-science 2051 stars on GitHub at the time of listing. The repository ships 1 skills in total. Homepage: https://www.aipoch.com
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