人腦類器官移植進小鼠，長出了四百萬人類神經元

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Would they be like the wild type controls or the apalial mice? You know, they're neither. They're so like in a third behavioral state.

它們會像野生型對照組，還是像無 pallium 小鼠？其實都不是。它們處在第三種行為狀態。

Sergio Pasca6:10

So now this tells us that it's likely the human cells that are causing this.

所以這告訴我們，很可能是人類細胞造成了這一點。

Sergio Pasca7:11

I want to say very clearly, this is not a human brain in a mouse.

我想非常明確地說，這不是小鼠體內的人腦。

Aparna Bhaduri9:12

So I think sometimes people wrongly think that regulation is a hindrance to scientists and I think that's a real mistake.

我認為有時人們錯誤地以為監管是對科學家的阻礙，我覺得這是個真正的錯誤。

Emily Jackson11:14

it doesn't really know how to generate the results or generate the figures or do the experiments or use the data and the code right because it doesn't have that hands-on experience

它其實並不知道怎麼生成結果、生成圖表、做實驗，或者使用數據和代碼，因為它沒有那種動手經驗。

James19:20

those two agents actually started talking to each other and they realized that they have some common interest and they can actually collaborate and in this case right they actually discovered a new splicing mutation associated with increases in risks for ADHD which is not known before

那兩個智能體真的開始互相交談，意識到彼此有共同興趣，可以合作，在這個案例裡它們真的發現了一個此前未知的、與 ADHD 風險升高相關的剪接突變。

James21:21

What is not clear to me from the paper whose responsibility it is to build this tool.

這篇論文沒有讓我看明白的一點是，建這個工具究竟是誰的責任。

Magdalena Skipper24:25

I think this is an opportunity for us to reimagine what knowledge can look like in the future, right? Does not have to be static artifacts could actually become this dynamic knowledge agents in some sense like a living knowledge right

我認為這是一個機會，讓我們重新想像未來的知識可以是什麼樣子。它不必是靜態的製品，而可以變成這種動態的知識智能體，某種意義上像活的知識。

James26:26

數字與實體

術語

organoid類器官

由人類幹細胞衍生、在培養皿中長成的三維腦樣組織小塊。

pallium外套（腦發育結構）

發育早期存在、之後發育成大腦皮層和海馬體的神經結構。

xenocortical mice異種皮層小鼠

論文中給接受人類皮層類器官移植的小鼠起的名字，意為皮層來自異種。

paper to agent論文轉智能體

把靜態論文復現並轉成可對話 AI 智能體的 workflow。

AlphaGenomeAlphaGenome

Google DeepMind 發布的、用於解讀不同突變效應的工具。

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